Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSA | P10619 | 1/20 | 0.33 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.32 |
| ▸ | SLC34A1 | Q06495 | 2/20 | 0.32 |
| ▸ | PDE2A | O00408 | 1/20 | 0.31 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.31 |
| ▸ | GRM8 | O00222 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.31 |
| ▸ | PTGES | O14684 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2032613 | 0.89 | SLC34A1 (0.36) | SLC34A1PTGES | |
| SCHEMBL1873473 | 0.86 | NPC1 (0.37) | CTSAPDE2APDE10AGRM8CYP1A2 | |
| SCHEMBL2034115 | 0.82 | PDE10A (0.39) | PDE10AGRM8CYP1A2GRM7 | |
| SCHEMBL2320981 | 0.81 | CTSA (0.31) | CTSAPDE2APDE10AGRM8CYP1A2 | |
| SCHEMBL2354029 | 0.81 | MEN1 (0.43) | GRM8CYP1A2GRM7 | |
| SCHEMBL2318082 | 0.81 | CTSA (0.32) | CTSAPDE2APDE10A | |
| SCHEMBL2039642 | 0.80 | SLC34A1 (0.32) | SLC34A1 | |
| SCHEMBL1162374 | 0.79 | CYP1A2 (0.37) | CTSAPDE2APDE10AGRM8CYP1A2 | |
| SCHEMBL2322215 | 0.79 | BACE1 (0.35) | — | |
| SCHEMBL2347440 | 0.76 | NPC1 (0.39) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076501-A1 | NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-30 | — | — | WO | claimed |
| WO-2011076501-A1 | NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-30 | — | — | WO | disclosed |