Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.37 |
| ▸ | GRM8 | O00222 | 1/20 | 0.37 |
| ▸ | GRM7 | Q14831 | 1/20 | 0.37 |
| ▸ | FPR1 | P21462 | 1/20 | 0.35 |
| ▸ | FPR2 | P25090 | 1/20 | 0.35 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.34 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.34 |
| ▸ | STIM1 | Q13586 | 1/20 | 0.34 |
| ▸ | ORAI1 | Q96D31 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.33 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.33 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2034329 | 0.89 | PDE10A (0.35) | PDE10A | |
| SCHEMBL1873473 | 0.86 | NPC1 (0.37) | PDE10ACYP1A2GRM8GRM7MAPT | |
| SCHEMBL2040686 | 0.82 | CTSA (0.33) | PDE10ACYP1A2GRM8GRM7 | |
| SCHEMBL2320981 | 0.81 | CTSA (0.31) | PDE10ACYP1A2GRM8GRM7 | |
| SCHEMBL2354029 | 0.81 | MEN1 (0.43) | CYP1A2GRM8GRM7FPR1FPR2 | |
| SCHEMBL2318082 | 0.81 | CTSA (0.32) | PDE10A | |
| SCHEMBL2040694 | 0.80 | PDE10A (0.41) | PDE10ACHEK1 | |
| SCHEMBL1162374 | 0.79 | CYP1A2 (0.37) | PDE10ACYP1A2GRM8GRM7CYP3A4 | |
| SCHEMBL2322215 | 0.79 | BACE1 (0.35) | FPR2 | |
| SCHEMBL2347440 | 0.76 | NPC1 (0.39) | CYP1A2PTGS2TSHRNPSR1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011076501-A1 | NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-30 | — | — | WO | claimed |
| WO-2011076501-A1 | NOVEL 5-(PYRIDIN-3-YL)-PYRIDANIZE DERIVATIVES AND THEIR USE AS MICROBICIDES | SYNGENTA PARTICIPATIONS AG (CH) | 2011-06-30 | — | — | WO | disclosed |