Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.61 |
| ▸ | ALOX12 | P18054 | 2/20 | 0.61 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.61 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.54 |
| ▸ | ACACB | O00763 | 7/20 | 0.52 |
| ▸ | HTR2A | P28223 | 5/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.47 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.47 |
| ▸ | DRD1 | P21728 | 1/20 | 0.47 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.47 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.47 |
| ▸ | HTR2C | P28335 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8219973 | 0.87 | MAPT (0.64) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL18398515 | 0.86 | MAPT (0.67) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL20404372 | 0.86 | ACACB (0.64) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL3032550 | 0.84 | MAPT (0.61) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL20404371 | 0.84 | MAPT (0.61) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL18412176 | 0.84 | MAPT (0.61) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL19845884 | 0.81 | MAPT (0.58) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL18398430 | 0.80 | MAPT (0.56) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL19845885 | 0.79 | NPC1 (0.56) | MAPTMEN1ALOX12KMT2ACTDSP1 | |
| SCHEMBL20731562 | 0.79 | MEN1 (0.54) | MAPTMEN1ALOX12KMT2ACTDSP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180208556-A1 | Method for Preparing Pimavanserin | SCI PHARMTECH, INC. (TW) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180208556-A1 | Method for Preparing Pimavanserin | PIM1, ALKBH1, PIM3 | MAPT 3958/4885MEN1 1509/4885ALOX12 3127/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.