Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.53 |
| ▸ | PRKDC | P78527 | 1/20 | 0.45 |
| ▸ | THRA | P10827 | 4/20 | 0.43 |
| ▸ | THRB | P10828 | 4/20 | 0.43 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.43 |
| ▸ | S1PR2 | O95136 | 1/20 | 0.43 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.43 |
| ▸ | LPAR2 | Q9HBW0 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.39 |
| ▸ | CYSLTR2 | Q9NS75 | 1/20 | 0.38 |
| ▸ | CYSLTR1 | Q9Y271 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2038528 | 1.00 | LMNA (0.53) | LMNAPRKDCTHRATHRBS1PR3 | |
| SCHEMBL2037034 | 1.00 | LMNA (0.53) | LMNAPRKDCTHRATHRBS1PR3 | |
| SCHEMBL2037716 | 0.98 | LMNA (0.54) | LMNAPRKDCTHRATHRBS1PR3 | |
| SCHEMBL2037945 | 0.94 | LMNA (0.56) | LMNAPRKDCTHRATHRBPOLB | |
| SCHEMBL30584237 | 0.92 | PTPN1 (0.47) | LMNAPRKDCTHRATHRBS1PR3 | |
| SCHEMBL29246741 | 0.92 | PTPN1 (0.47) | LMNAPRKDCTHRATHRBS1PR3 | |
| SCHEMBL31078471 | 0.90 | LMNA (0.44) | LMNAS1PR3KDM4EMEN1GAA | |
| SCHEMBL18901651 | 0.90 | LMNA (0.44) | LMNAS1PR3KDM4EMEN1GAA | |
| SCHEMBL278733 | 0.90 | LMNA (0.44) | LMNAS1PR3KDM4EMEN1GAA | |
| SCHEMBL26103495 | 0.90 | LMNA (0.44) | LMNAS1PR3KDM4EMEN1GAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8525131-B2 | Phosphorescent organic compounds | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2013-09-03 | — | — | US | claimed |
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2012-10-04 | — | — | US | claimed |
| WO-2011066415-A2 | PHOSPHORESCENT ORGANIC COMPOUNDS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2011-06-03 | — | — | WO | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120248337-A1 | PHOSPHORESCENT ORGANIC COMPOUNDS | PAICS, PPIP5K2, PPA1 | LMNA 3394/4885PRKDC 2103/4885THRA 3970/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.