Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GSR | P00390 | 1/20 | 0.42 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.41 |
| ▸ | CPB2 | Q96IY4 | 5/20 | 0.40 |
| ▸ | PAOX | Q6QHF9 | 2/20 | 0.35 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
| ▸ | GNAI1 | P63096 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.33 |
| ▸ | CHRNB2 | P17787 | 1/20 | 0.33 |
| ▸ | CHRNB4 | P30926 | 1/20 | 0.33 |
| ▸ | CHRNA3 | P32297 | 1/20 | 0.33 |
| ▸ | CHRNA4 | P43681 | 1/20 | 0.33 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.33 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA2 | P00918 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20411609 | 1.00 | GSR (0.42) | GSRRNPEPCPB2PAOXGNAI3 | |
| SCHEMBL2280438 | 1.00 | GSR (0.42) | GSRRNPEPCPB2PAOXGNAI3 | |
| SCHEMBL20414864 | 1.00 | GSR (0.42) | GSRRNPEPCPB2PAOXGNAI3 | |
| SCHEMBL20411610 | 1.00 | GSR (0.42) | GSRRNPEPCPB2PAOXGNAI3 | |
| SCHEMBL20411601 | 1.00 | GSR (0.42) | GSRRNPEPCPB2PAOXGNAI3 | |
| SCHEMBL8183812 | 0.94 | CPB2 (0.36) | GSRRNPEPCPB2PAOXCHRNB2 | |
| SCHEMBL8183821 | 0.94 | CPB2 (0.36) | GSRRNPEPCPB2PAOXCHRNB2 | |
| SCHEMBL11326837 | 0.85 | GABRR1 (0.39) | CHRNB2CHRNB4CHRNA3CHRNA4CA1 | |
| SCHEMBL17642018 | 0.83 | CPB2 (0.43) | GSRRNPEPCPB2PAOXGNAI3 | |
| SCHEMBL13930214 | 0.83 | CPB2 (0.43) | GSRRNPEPCPB2PAOXGNAI3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230132372-A9 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
| US-20230132372-A9 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2023-04-27 | — | — | US | disclosed |
| US-20220018847-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2022-01-20 | — | — | US | disclosed |
| US-20200174007-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2020-06-04 | — | — | US | disclosed |
| US-20180209985-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-07-26 | — | — | US | disclosed |
| US-20180209985-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2018-07-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20200174007-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | GSR 3802/4885RNPEP 1103/4885CPB2 2254/4885 |
| US-20230132372-A9 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | GSR 3802/4885RNPEP 1103/4885CPB2 2254/4885 |
| US-20180209985-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | GSR 3802/4885RNPEP 1103/4885CPB2 2254/4885 |
| US-20220018847-A1 | REAGENTS FOR QUANTITATIVE MASS SPECTROMETRY | CHAMP1, SRMS, QPCTL | GSR 3802/4885RNPEP 1103/4885CPB2 2254/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.