Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 2/20 | 0.59 |
| ▸ | CCR5 | P51681 | 2/20 | 0.59 |
| ▸ | CCR8 | P51685 | 2/20 | 0.59 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | NOS3 | P29474 | 1/20 | 0.37 |
| ▸ | NOS1 | P29475 | 1/20 | 0.37 |
| ▸ | NOS2 | P35228 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 2/20 | 0.37 |
| ▸ | ABL1 | P00519 | 4/20 | 0.34 |
| ▸ | BCR | P11274 | 4/20 | 0.34 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.34 |
| ▸ | GRM5 | P41594 | 1/20 | 0.34 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL198098 | 0.85 | CCR1 (0.81) | CCR1CCR5CCR8CYP2A6METAP2 | |
| SCHEMBL29875378 | 0.79 | — | — | |
| SCHEMBL457223 | 0.79 | — | — | |
| SCHEMBL20412761 | 0.79 | CCR1 (0.53) | CCR1CCR5CCR8CYP2A6METAP2 | |
| SCHEMBL29397106 | 0.77 | CCR1 (1.00) | CCR1CCR5CCR8CYP2A6METAP2 | |
| SCHEMBL181893 | 0.77 | CCR1 (1.00) | CCR1CCR5CCR8CYP2A6METAP2 | |
| SCHEMBL29943121 | 0.77 | CCR1 (0.65) | CCR1CCR5CCR8CYP2A6METAP2 | |
| SCHEMBL18775529 | 0.77 | CCR1 (0.65) | CCR1CCR5CCR8CYP2A6METAP2 | |
| SCHEMBL1508069 | 0.77 | CCR1 (0.65) | CCR1CCR5CCR8CYP2A6METAP2 | |
| SCHEMBL24683565 | 0.76 | CCR1 (0.71) | CCR1CCR5CCR8CYP2A6METAP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134847-A1 | IMMUNOSUPPRESSIVE AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-07-26 | — | — | WO | disclosed |