Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCR1 | P32246 | 1/20 | 0.53 |
| ▸ | CCR5 | P51681 | 1/20 | 0.53 |
| ▸ | CCR8 | P51685 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.50 |
| ▸ | METAP2 | P50579 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.39 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.39 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | UHRF1 | Q96T88 | 1/20 | 0.36 |
| ▸ | PLAU | P00749 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | NOS3 | P29474 | 1/20 | 0.34 |
| ▸ | NOS1 | P29475 | 1/20 | 0.34 |
| ▸ | NOS2 | P35228 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | SYK | P43405 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23909426 | 0.81 | KDM4E (0.54) | CCR1CCR5CCR8HSP90AA1KDM4E | |
| SCHEMBL20412648 | 0.79 | CCR1 (0.59) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL198098 | 0.77 | CCR1 (0.81) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL31482988 | 0.75 | CCR1 (0.94) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL7229668 | 0.73 | CCR1 (0.50) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL7229664 | 0.73 | CCR1 (0.50) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL29397106 | 0.73 | CCR1 (1.00) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL181893 | 0.73 | CCR1 (1.00) | CCR1CCR5CCR8METAP2KDM4E | |
| SCHEMBL6792348 | 0.72 | GAA (0.44) | HSP90AA1KDM4EL3MBTL1ALOX15GAA | |
| SCHEMBL24683565 | 0.72 | CCR1 (0.71) | CCR1CCR5CCR8METAP2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018134847-A1 | IMMUNOSUPPRESSIVE AGENTS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2018-07-26 | — | — | WO | disclosed |