Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TGFBR1 | P36897 | 1/20 | 0.35 |
| ▸ | POLB | P06746 | 2/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.31 |
| ▸ | CTSK | P43235 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13862886 | 0.86 | TGFBR1 (0.35) | TGFBR1KDM4EALDH1A1TDP1 | |
| SCHEMBL16443433 | 0.83 | TGFBR1 (0.33) | TGFBR1ALDH1A1 | |
| SCHEMBL13862863 | 0.83 | TGFBR1 (0.33) | TGFBR1ALDH1A1 | |
| SCHEMBL4560265 | 0.81 | SMN1; SMN2 (0.35) | POLBL3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL1348161 | 0.79 | POLB (0.35) | TGFBR1POLBL3MBTL1KDM4EALDH1A1 | |
| SCHEMBL16443268 | 0.79 | CA2 (0.34) | TGFBR1 | |
| SCHEMBL13862890 | 0.79 | SMN1; SMN2 (0.45) | TGFBR1L3MBTL1KDM4ESMN1; SMN2LMNA | |
| SCHEMBL3232710 | 0.79 | TGFBR1 (0.36) | TGFBR1KDM4ESMN1; SMN2ALDH1A1TDP1 | |
| SCHEMBL6240859 | 0.79 | TGFBR1 (0.36) | TGFBR1KDM4EALDH1A1TDP1 | |
| SCHEMBL21504381 | 0.78 | TGFBR1 (0.33) | TGFBR1POLBSMN1; SMN2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 36 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20120305838-A1 | Polyelectrolyte-Coated Size-Exclusion Ion-Exchange Particles | APPLIED BIOSYSTEMS, LLC (US) | 2012-12-06 | — | — | US | claimed |
| EP-2277987-A2 | Polyelectrolyte-coated size-exclusion ion-exchange particles | Life Technologies Corporation (US) | 2011-01-26 | — | — | EP | claimed |
| US-20100317841-A1 | Polyelectrolyte-Coated Size-Exclusion Ion-Exchange Particles | Life Technologies Corporation (US) | 2010-12-16 | — | — | US | claimed |
| US-20050181378-A1 | For PCR and DNA sequencing; electrophoresis; microfluidics | APPLERA CORPORATION (US) | 2005-08-18 | — | — | US | claimed |
| US-10087273-B2 | Multifunctional polymers | ISP INVESTMENTS LLC (US) | 2018-10-02 | — | — | US | disclosed |
| US-20160214102-A1 | Vacuum Assist for a Microplate | APPLIED BIOSYSTEMS LLC (US) | 2016-07-28 | — | — | US | disclosed |
| US-9052298-B2 | High density plate filler | APPLIED BIOSYSTEMS, LLC (US) | 2015-06-09 | — | — | US | disclosed |
| US-20150044161-A1 | MULTIFUNCTIONAL POLYMERS | ISP INVESTMENTS INC. (US) | 2015-02-12 | — | — | US | disclosed |
| US-20140287416-A1 | POLYELECTROLYTE-COATED SIZE-EXCLUSION ION-EXCHANGE PARTICLES | APPLIED BIOSYSTEMS LLC (US) | 2014-09-25 | — | — | US | disclosed |
| US-8638509-B2 | Optical camera alignment | APPLIED BIOSYSTEMS, LLC (US) | 2014-01-28 | — | — | US | disclosed |
| US-20130210674-A1 | WHOLE GENOME EXPRESSION ANALYSIS SYSTEM | Life Technologies Corporation (US) | 2013-08-15 | — | — | US | disclosed |
| US-20120305838-A1 | Polyelectrolyte-Coated Size-Exclusion Ion-Exchange Particles | APPLIED BIOSYSTEMS, LLC (US) | 2012-12-06 | — | — | US | disclosed |
| US-20060160122-A1 | For separating PCR reaction products and/or DNA sequencing reaction products; kits | APPLERA CORPORATION (US) | 2006-07-20 | — | — | US | disclosed |
| US-20050232818-A1 | Single sheet seal applicator and cartridge | APPLIED BIOSYSTEMS, LLC | 2005-10-20 | — | — | US | disclosed |
| US-20050232822-A1 | microtiter plates; assay; genomics | APPLIED BIOSYSTEMS, INC. | 2005-10-20 | — | — | US | disclosed |
| US-20050226780-A1 | Manual seal applicator | APPLIED BIOSYSTEMS, LLC | 2005-10-13 | — | — | US | disclosed |
| US-20050221358-A1 | Pressure chamber clamp mechanism | APPLIED BIOSYSTEMS, LLC | 2005-10-06 | — | — | US | disclosed |
| US-20050181378-A1 | For PCR and DNA sequencing; electrophoresis; microfluidics | APPLERA CORPORATION (US) | 2005-08-18 | — | — | US | disclosed |
| EP-0403638-A1 | POLYMERISABLE COMPOSITION | KODAK LIMITED (GB) | 1990-12-27 | — | — | EP | disclosed |
| WO-1990007527-A1 | POLYMERISABLE COMPOSITION | KODAK LIMITED (GB) | 1990-07-12 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20150044161-A1 | MULTIFUNCTIONAL POLYMERS | PUF60, PARG, PARN | TGFBR1 4665/4885POLB 550/4885L3MBTL1 768/4885 |
| US-10087273-B2 | Multifunctional polymers | PUF60, PARG, PARN | TGFBR1 4665/4885POLB 550/4885L3MBTL1 768/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.