Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHODH | Q02127 | 1/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | USP2 | O75604 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.51 |
| ▸ | GLA | P06280 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | MAPT | P10636 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | TACR3 | P29371 | 2/20 | 0.50 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.50 |
| ▸ | TLR8 | Q9NR97 | 7/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | MOK | Q9UQ07 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9988793 | 0.98 | DHODH (0.53) | DHODHHPGDKDM4EUSP2ALDH1A1 | |
| SCHEMBL27917367 | 0.94 | DHODH (0.58) | DHODHHPGDTACR3SLC2A1TLR8 | |
| SCHEMBL20414364 | 0.85 | ACHE (0.53) | DHODHHPGDKDM4ESLC2A1TLR8 | |
| SCHEMBL8675109 | 0.83 | ACHE (0.50) | DHODHHPGDKDM4ETACR3SLC2A1 | |
| SCHEMBL8091105 | 0.83 | ACHE (0.54) | DHODHHPGDKDM4ESLC2A1TLR8 | |
| Phthalic Acid SCHEMBL28229283 | 0.82 | DHODH (0.56) | DHODHHPGDKDM4EUSP2ALDH1A1 | |
| SCHEMBL28118267 | 0.82 | KDM4E (0.43) | DHODHHPGDKDM4EUSP2ALDH1A1 | |
| SCHEMBL27367367 | 0.81 | ACHE (0.51) | DHODHHPGDKDM4ETACR3SLC2A1 | |
| Phthalic Acid SCHEMBL28034650 | 0.81 | DHODH (0.55) | DHODHHPGDKDM4EUSP2ALDH1A1 | |
| SCHEMBL13243228 | 0.80 | ESRRB (0.59) | DHODHHPGDKDM4EALDH1A1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018132905-A1 | COMPOUNDS FOR TREATMENT OF GLIOBLASTOMA | THE GOVERNORS OF THE UNIVERSITY OF ALBERTA (CA) | 2018-07-26 | — | — | WO | disclosed |