Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 1/20 | 0.51 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | DHODH | Q02127 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | ACACA | Q13085 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | TACR3 | P29371 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27917367 | 0.84 | DHODH (0.58) | ACHESLC2A1LMNASMN1; SMN2HPGD | |
| SCHEMBL7450288 | 0.83 | ACHE (0.58) | ACHESLC2A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL8091105 | 0.83 | ACHE (0.54) | ACHESLC2A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL9988793 | 0.83 | DHODH (0.53) | ACHESLC2A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL8675109 | 0.83 | ACHE (0.50) | ACHESLC2A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL20414372 | 0.81 | DHODH (0.52) | ACHESLC2A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL20414364 | 0.81 | ACHE (0.53) | ACHESLC2A1LMNASMN1; SMN2KDM4E | |
| SCHEMBL10674581 | 0.80 | PDE10A (0.55) | LMNASMN1; SMN2KDM4EPDE10ADHODH | |
| SCHEMBL10673312 | 0.79 | PDE10A (0.54) | LMNASMN1; SMN2KDM4EPDE10ADHODH | |
| Bromide SCHEMBL4455959 | 0.79 | ACHE (0.53) | ACHESLC2A1LMNASMN1; SMN2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-1088709-C | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 2002-08-07 | — | — | CN | disclosed |
| CN-1052984-C | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 2000-05-31 | — | — | CN | disclosed |
| CN-1229082-A | Amine compound and its acid addition salt | ROUSSEL UCLAF (FR) | 1999-09-22 | — | — | CN | disclosed |
| CN-1151746-A | Novel erythromycin derivatives, process for their preparation and their use as medicaments | ROUSSEL UCLAF (FR) | 1997-06-11 | — | — | CN | disclosed |