SCHEMBL20414723

SCHEMBL20414723

C=C(CC(C)(CC(C)(CC(C)(C)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1)c1ccc(O)cc1

nearest known ligand 0.50

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SHBG P04278 1/20 0.50
ESR1 P03372 11/20 0.41
ESR2 Q92731 11/20 0.41
ESRRG P62508 4/20 0.36
CYP3A4 P08684 4/20 0.36
HSD17B10 Q99714 3/20 0.36
LMNA P02545 2/20 0.36
AR P10275 2/20 0.36
TSHR P16473 2/20 0.36
SLC6A2 P23975 2/20 0.36
SLC6A4 P31645 2/20 0.36
HTR6 P50406 2/20 0.36
SLC6A3 Q01959 2/20 0.36
TYR P14679 1/20 0.36
HPGD P15428 1/20 0.36
ALDH1A1 P00352 3/20 0.34
MAPT P10636 2/20 0.34
MEN1 O00255 1/20 0.34
NR1I2 O75469 1/20 0.34
USP2 O75604 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL733201 0.97 SHBG (0.53) SHBGESR1ESR2ESRRGCYP3A4
SCHEMBL29113544 0.84 SHBG (0.41) SHBGESR1ESR2CYP3A4LMNA
SCHEMBL3419256 0.84 SHBG (0.53) SHBGESR1ESR2ESRRGCYP3A4
SCHEMBL1201797 0.83 SHBG (0.69) SHBGESR1ESR2ESRRGCYP3A4
SCHEMBL6060401 0.82 SHBG (0.72) SHBGESR1ESR2ESRRGCYP3A4
SCHEMBL7172775 0.80 CYP2C19 (0.44) SHBGESR1ESR2CYP3A4ALDH1A1
SCHEMBL4838732 0.78 ESR1 (0.57) SHBGESR1ESR2ESRRGCYP3A4
SCHEMBL11834731 0.77 SHBG (0.33) SHBG
SCHEMBL6523350 0.74 SHBG (0.32) SHBG
SCHEMBL9244771 0.71 SHBG (0.51) SHBGESR1ESR2ESRRGCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3571240-B1 REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES BV (NL) 2023-08-30 EP disclosed
US-11312822-B2 Reduced color polycarbonate compositions, methods of manufacture, and articles thereof SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2022-04-26 US disclosed
US-20210292477-A1 REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2021-09-23 US disclosed
WO-2018134734-A1 REDUCED COLOR POLYCARBONATE COMPOSITIONS, METHODS OF MANUFACTURE, AND ARTICLES THEREOF SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2018-07-26 WO disclosed