Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SHBG | P04278 | 1/20 | 0.51 |
| ▸ | ESR1 | P03372 | 13/20 | 0.42 |
| ▸ | ESR2 | Q92731 | 12/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.37 |
| ▸ | LMNA | P02545 | 2/20 | 0.37 |
| ▸ | AR | P10275 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 2/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | TSHR | P16473 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | HTR6 | P50406 | 1/20 | 0.37 |
| ▸ | ESRRG | P62508 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | PGR | P06401 | 1/20 | 0.34 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6157069 | 0.86 | SHBG (0.50) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL1201797 | 0.85 | SHBG (0.69) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL6060401 | 0.83 | SHBG (0.72) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL18139 | 0.83 | SHBG (0.53) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL9220135 | 0.79 | SHBG (0.40) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL8625814 | 0.78 | SHBG (0.39) | SHBGESR1ESR2CYP3A4CYP2C9 | |
| SCHEMBL5174803 | 0.76 | SHBG (0.38) | SHBGESR1ESR2 | |
| SCHEMBL5140991 | 0.76 | SHBG (0.45) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL2143217 | 0.74 | ESR1 (0.47) | SHBGESR1ESR2CYP3A4LMNA | |
| SCHEMBL29113544 | 0.72 | SHBG (0.41) | SHBGESR1ESR2CYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5407966-A | Recyclable thermoplastic foam with a high glass transition temperature II | BAYER AKTIENGESELLSCHAFT (DE) | 1995-04-18 | — | — | US | disclosed |