SCHEMBL20416950

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL30402006	1.00	ADORA2A (0.41)	ADORA2AADORA1ADORA2BKLKB1CYP19A1
	SCHEMBL20416769	0.91	ADORA2B (0.41)	ADORA2AADORA1ADORA2BKLKB1CYP19A1
	SCHEMBL30401160	0.91	ADORA2B (0.41)	ADORA2AADORA1ADORA2BKLKB1CYP19A1
	SCHEMBL20436714	0.90	ADORA2A (0.45)	ADORA2AADORA1ADORA2BKLKB1CYP19A1
	SCHEMBL30402211	0.88	ADORA2A (0.49)	ADORA2AADORA1ADORA2B
	SCHEMBL20400534	0.88	ADORA2A (0.49)	ADORA2AADORA1ADORA2B
	SCHEMBL20416734	0.87	CYP19A1 (0.41)	ADORA2AADORA1ADORA2BKLKB1CYP19A1
	SCHEMBL30401212	0.87	CYP19A1 (0.41)	ADORA2AADORA1ADORA2BKLKB1CYP19A1
	SCHEMBL20401228	0.83	ADORA2A (0.39)	ADORA2AADORA1ADORA2BCYP19A1OXTR
	SCHEMBL20401313	0.83	ADORA2A (0.39)	ADORA2AADORA1ADORA2BCYP19A1OXTR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (6 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.