Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP19A1 | P11511 | 1/20 | 0.41 |
| ▸ | KLKB1 | P03952 | 1/20 | 0.40 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.40 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.40 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 1/20 | 0.39 |
| ▸ | OXTR | P30559 | 1/20 | 0.39 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | ADORA2B | P29275 | 7/20 | 0.38 |
| ▸ | ADORA2A | P29274 | 4/20 | 0.38 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.38 |
| ▸ | TEK | Q02763 | 2/20 | 0.37 |
| ▸ | KDR | P35968 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | CD74 | P04233 | 1/20 | 0.36 |
| ▸ | MIF | P14174 | 1/20 | 0.36 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20416734 | 1.00 | CYP19A1 (0.41) | CYP19A1KLKB1HDAC2HDAC8HDAC6 | |
| SCHEMBL20416769 | 0.93 | ADORA2B (0.41) | CYP19A1KLKB1HDAC2HDAC8HDAC6 | |
| SCHEMBL30401160 | 0.93 | ADORA2B (0.41) | CYP19A1KLKB1HDAC2HDAC8HDAC6 | |
| SCHEMBL20416723 | 0.90 | CYP19A1 (0.43) | CYP19A1KLKB1HDAC2HDAC8HDAC6 | |
| SCHEMBL30402211 | 0.88 | ADORA2A (0.49) | ADORA2BADORA2AADORA1 | |
| SCHEMBL20400534 | 0.88 | ADORA2A (0.49) | ADORA2BADORA2AADORA1 | |
| SCHEMBL20417082 | 0.88 | CTSS (0.50) | CYP19A1KLKB1HDAC2HDAC8HDAC6 | |
| SCHEMBL20416950 | 0.87 | ADORA2A (0.41) | CYP19A1KLKB1HDAC2HDAC8HDAC6 | |
| SCHEMBL30402006 | 0.87 | ADORA2A (0.41) | CYP19A1KLKB1HDAC2HDAC8HDAC6 | |
| SCHEMBL20417073 | 0.86 | KLKB1 (0.39) | CYP19A1KLKB1HDAC2HDAC8HDAC6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116768859-A | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-09-19 | — | — | CN | disclosed |
| CN-110214012-B | Azolopyrimidines for the treatment of cancer related disorders | 艾库斯生物科学有限公司 | 2023-05-09 | — | — | CN | disclosed |