Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADK | P55263 | 14/20 | 0.61 |
| ▸ | HASPIN | Q8TF76 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | MTOR | P42345 | 1/20 | 0.54 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.48 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.48 |
| ▸ | STING1 | Q86WV6 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | GALR3 | O60755 | 1/20 | 0.46 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3768787 | 1.00 | ADK (0.61) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL13068771 | 1.00 | ADK (0.61) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL29363011 | 0.88 | ADK (0.55) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL14154378 | 0.88 | ADK (0.60) | ADKHASPINRAB9AMTORSLC29A1 | |
| SCHEMBL20419234 | 0.86 | ADK (0.59) | ADK | |
| SCHEMBL20419136 | 0.86 | ADK (0.59) | ADK | |
| SCHEMBL14134801 | 0.86 | PRMT5 (0.48) | ADKRAB9APRMT5WDR77DOT1L | |
| SCHEMBL20938262 | 0.86 | ADK (0.59) | ADK | |
| SCHEMBL20938333 | 0.86 | ADK (0.46) | ADKRAB9APRMT5DOT1LNPC1 | |
| SCHEMBL22912603 | 0.86 | PRMT5 (0.48) | ADKRAB9APRMT5WDR77DOT1L |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018133854-A1 | ADENOSINE ANALOG AND ITS USE IN REGULATING THE CIRCADIAN CLOCK | NATIONAL INSTITUTE OF BIOLOGICAL SCIENCES, BEIJING (CN) | 2018-07-26 | — | — | WO | disclosed |