Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | MMP2 | P08253 | 1/20 | 0.36 |
| ▸ | MMP13 | P45452 | 1/20 | 0.36 |
| ▸ | MMP14 | P50281 | 1/20 | 0.36 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.35 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | RECQL | P46063 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 2/20 | 0.33 |
| ▸ | RAB9A | P51151 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL15784496 | 0.82 | MAPK1 (0.39) | KDM4EALDH1A1MAPK1MMP2MMP13 | |
| SCHEMBL13837541 | 0.81 | MAPK1 (0.38) | KDM4EALDH1A1MAPK1MMP2MMP13 | |
| SCHEMBL20419554 | 0.81 | KDM4E (0.40) | KDM4EALOX15L3MBTL1ALDH1A1MAPK1 | |
| SCHEMBL28857790 | 0.76 | MMP2 (0.40) | KDM4EALDH1A1MAPK1MMP2MMP13 | |
| SCHEMBL2246566 | 0.73 | BAZ2B (0.62) | KDM4EALDH1A1MAPK1MMP2MMP13 | |
| SCHEMBL295558 | 0.73 | MAPK1 (0.42) | KDM4EL3MBTL1ALDH1A1MAPK1MMP2 | |
| SCHEMBL69696 | 0.73 | MEN1 (0.44) | KDM4EL3MBTL1ALDH1A1MAPK1BAZ2B | |
| SCHEMBL17159047 | 0.72 | NPC1 (0.36) | KDM4EALDH1A1MAPK1MMP2MMP13 | |
| SCHEMBL17159046 | 0.72 | NPC1 (0.36) | KDM4EALDH1A1MAPK1MMP2MMP13 | |
| SCHEMBL24915278 | 0.71 | MEN1 (0.42) | KDM4EALDH1A1MAPK1MMP2MMP13 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018133730-A1 | HETEROCYCLIC COMPOUND, PREPARATION METHOD AND USE THEREFOR | 四川科伦博泰生物医药股份有限公司 | 2018-07-26 | — | — | WO | disclosed |