Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP2 | P08253 | 1/20 | 0.40 |
| ▸ | MMP13 | P45452 | 1/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.39 |
| ▸ | BAZ2B | Q9UIF8 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.37 |
| ▸ | HPGD | P15428 | 2/20 | 0.37 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.35 |
| ▸ | MEN1 | O00255 | 2/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | PKM | P14618 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | JMJD6 | Q6NYC1 | 1/20 | 0.34 |
| ▸ | PLAT | P00750 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27415147 | 0.81 | MMP2 (0.35) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL21603990 | 0.81 | MMP2 (0.35) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL2246566 | 0.77 | BAZ2B (0.62) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL295558 | 0.77 | MAPK1 (0.42) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL69696 | 0.77 | MEN1 (0.44) | MAPK1BAZ2BALDH1A1KDM4EHPGD | |
| SCHEMBL20419546 | 0.76 | KDM4E (0.42) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL24915278 | 0.75 | MEN1 (0.42) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL1312720 | 0.75 | MAPK1 (0.41) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL1314210 | 0.75 | MAPT (0.41) | MMP2MMP13MMP14MAPK1BAZ2B | |
| SCHEMBL478715 | 0.75 | MAPK1 (0.41) | MMP2MMP13MMP14MAPK1BAZ2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-105001225-B | The heterocyclic modulators of lipid synthesis | 3-V 生物科学公司 | 2018-04-06 | — | — | CN | disclosed |