SCHEMBL20419702

SCHEMBL20419702

BC(C)(C)C(C)(CCCCCC)CCCCCC

nearest known ligand 0.42

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.42
THRB P10828 1/20 0.42
GGPS1 O95749 6/20 0.38
FDPS P14324 9/20 0.37
SMPD1 P17405 2/20 0.35
CES2 O00748 1/20 0.35
LPAR1 Q92633 1/20 0.35
LPAR3 Q9UBY5 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20419587 1.00 TSHR (0.42) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL24828891 0.97 TSHR (0.40) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL20419605 0.97 TSHR (0.40) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL19565503 0.80 FDPS (0.43) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL20419701 0.80 TSHR (0.38) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL20419640 0.80 TSHR (0.38) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL18874524 0.80 FDPS (0.43) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL20419733 0.80 TSHR (0.38) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL20419657 0.79 TSHR (0.42) TSHRTHRBGGPS1FDPSSMPD1
SCHEMBL20419619 0.79 LMNA (0.30) TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11545637-B2 Organic electroluminescent materials and devices UNIVERSAL DISPLAY CORPORATION (US) 2023-01-03 US disclosed
US-20180212163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES UNIVERSAL DISPLAY CORPORATION (US) 2018-07-26 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180212163-A1 ORGANIC ELECTROLUMINESCENT MATERIALS AND DEVICES OCIAD2, OCIAD1, ICOSLG TSHR 3156/4885THRB 4207/4885GGPS1 2636/4885
US-11545637-B2 Organic electroluminescent materials and devices OCIAD2, OCIAD1, ICOSLG TSHR 3156/4885THRB 4207/4885GGPS1 2636/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.