Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | S1PR5 | Q9H228 | 8/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | GAA | P10253 | 2/20 | 0.44 |
| ▸ | THRB | P10828 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | USP2 | O75604 | 1/20 | 0.44 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.44 |
| ▸ | APEX1 | P27695 | 1/20 | 0.44 |
| ▸ | APOBEC3A | P31941 | 1/20 | 0.44 |
| ▸ | RECQL | P46063 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20421068 | 0.89 | S1PR5 (0.49) | S1PR5S1PR1ALDH1A1GAATHRB | |
| SCHEMBL20420921 | 0.86 | ALDH1A1 (0.46) | S1PR5S1PR1ALDH1A1GAATHRB | |
| SCHEMBL17078484 | 0.85 | KDM4E (0.52) | ALDH1A1GAASMN1; SMN2KDM4EMEN1 | |
| SCHEMBL17078881 | 0.85 | HDAC6 (0.58) | KDM1AHDAC1HDAC6 | |
| SCHEMBL20421155 | 0.85 | ALDH1A1 (0.57) | S1PR5S1PR1ALDH1A1SMN1; SMN2KDM4E | |
| SCHEMBL20432867 | 0.85 | HDAC6 (0.58) | KDM1AHDAC1HDAC6 | |
| SCHEMBL20421014 | 0.85 | POLB (0.46) | S1PR5S1PR1ALDH1A1GAATHRB | |
| SCHEMBL20421188 | 0.85 | L3MBTL1 (0.47) | S1PR5S1PR1ALDH1A1GAATHRB | |
| SCHEMBL20421018 | 0.83 | S1PR5 (0.51) | S1PR5S1PR1ALDH1A1GAASMN1; SMN2 | |
| SCHEMBL20421074 | 0.83 | HDAC1 (0.49) | S1PR5S1PR1ALDH1A1GAATHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3116859-B1 | NOVEL COMPOUNDS AS HISTONE DEACETYLASE 6 INHIBITORS AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | CHONG KUN DANG PHARMACEUTICAL CORP (KR) | 2018-08-01 | — | — | EP | disclosed |