Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL20423664 | 0.77 | CA1 (0.42) | — | |
| Bicarbonate SCHEMBL27793478 | 0.73 | FFAR3 (0.50) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL1058643 | 0.73 | FFAR3 (0.50) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL20423493 | 0.71 | FFAR3 (0.33) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL20423711 | 0.71 | FFAR3 (0.33) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL20423710 | 0.70 | FFAR3 (0.46) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL10180649 | 0.70 | FFAR3 (0.46) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL20423500 | 0.69 | FFAR3 (0.38) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL20423459 | 0.69 | FFAR3 (0.32) | FFAR3LCKFYN | |
| Bicarbonate SCHEMBL27133010 | 0.69 | TP53 (0.32) | FFAR3LCKFYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11043699-B2 | Nonaqueous electrolyte solution and method for producing nonaqueous electrolyte secondary battery | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2021-06-22 | — | — | US | disclosed |
| US-20180219259-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND METHOD FOR PRODUCING NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | TOYOTA JIDOSHA KABUSHIKI KAISHA (JP) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11043699-B2 | Nonaqueous electrolyte solution and method for producing nonaqueous electrolyte secondary battery | NAF1, CA2, CA1 | FFAR3 3077/4885LCK 3570/4885FYN 2540/4885 |
| US-20180219259-A1 | NONAQUEOUS ELECTROLYTE SOLUTION AND METHOD FOR PRODUCING NONAQUEOUS ELECTROLYTE SECONDARY BATTERY | NAF1, CA2, CA1 | FFAR3 3077/4885LCK 3570/4885FYN 2540/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.