SCHEMBL20423846

SCHEMBL20423846

O/N=C1/CCc2c(cnn2Cc2ccccc2)C1

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
AADAT Q8N5Z0 1/20 0.40
RECQL P46063 1/20 0.40
TSHR P16473 2/20 0.38
ALDH1A1 P00352 3/20 0.36
HDAC9 Q9UKV0 3/20 0.36
MEN1 O00255 1/20 0.34
KMT2A Q03164 1/20 0.34
MAPT P10636 2/20 0.33
HSD17B10 Q99714 2/20 0.33
KDM4E B2RXH2 1/20 0.33
HPGD P15428 1/20 0.33
MAPK1 P28482 1/20 0.33
CASP1 P29466 1/20 0.33
CASP7 P55210 1/20 0.33
ATM Q13315 1/20 0.33
TDP1 Q9NUW8 1/20 0.33
L3MBTL1 Q9Y468 1/20 0.33
PKM P14618 1/20 0.33
GPR55 Q9Y2T6 1/20 0.33
POLB P06746 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL20434822 1.00 AADAT (0.40) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL20423847 1.00 AADAT (0.40) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL17338762 0.73 AADAT (0.47) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL3895432 0.71 RECQL (0.41) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL6110305 0.70 RECQL (0.43) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL20423851 0.70 AADAT (0.40) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL20423850 0.70 AADAT (0.40) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL2076196 0.69 HTR7 (0.61) MEN1KMT2A
SCHEMBL24365390 0.68 AADAT (0.46) AADATRECQLTSHRALDH1A1HDAC9
SCHEMBL24365386 0.68 AADAT (0.46) AADATRECQLTSHRALDH1A1HDAC9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3357914-B1 AROMATIC COMPOUND PRODUCTION METHOD FUJIFILM CORP (JP) 2019-11-20 EP disclosed
US-10323005-B2 Aromatic compound production method FUJIFILM CORPORATION (JP) 2019-06-18 US disclosed
EP-3357914-A1 AROMATIC COMPOUND PRODUCTION METHOD FUJIFILM Corporation (JP) 2018-08-08 EP disclosed
US-20180215716-A1 AROMATIC COMPOUND PRODUCTION METHOD FUJIFILM CORPORATION (JP) 2018-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180215716-A1 AROMATIC COMPOUND PRODUCTION METHOD PAH, AHR, TYR AADAT 44/4885RECQL 955/4885TSHR 3521/4885
US-10323005-B2 Aromatic compound production method PAH, AHR, TYR AADAT 44/4885RECQL 955/4885TSHR 3521/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.