Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | PLA2G2A | P14555 | 2/20 | 0.41 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | HTT | P42858 | 2/20 | 0.40 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.40 |
| ▸ | MET | P08581 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.39 |
| ▸ | ABL1 | P00519 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20424055 | 0.86 | TP53 (0.40) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL20442235 | 0.80 | NR4A2 (0.47) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL20442234 | 0.78 | ABL1 (0.50) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL17442551 | 0.78 | NR4A2 (0.45) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL20424058 | 0.70 | KDM4E (0.48) | MAPTKDM4EALDH1A1HTTSMN1; SMN2 | |
| SCHEMBL31413729 | 0.68 | PLA2G2A (0.46) | MAPTKDM4EMEN1KMT2AGAA | |
| SCHEMBL19682925 | 0.67 | OPRK1 (0.44) | KDM4EGAANR4A2ALDH1A1TSHR | |
| SCHEMBL4160132 | 0.67 | OPRK1 (0.44) | KDM4EMEN1KMT2ANR4A2ALDH1A1 | |
| SCHEMBL8784322 | 0.67 | PLA2G2A (0.60) | KDM4EMEN1KMT2APLA2G2AALDH1A1 | |
| SCHEMBL19437639 | 0.66 | ABL1 (0.51) | MEN1KMT2ANR4A2ALDH1A1HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138050-A1 | CONDENSED BICYCLIC HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-02 | — | — | WO | disclosed |
| WO-2018138050-A1 | CONDENSED BICYCLIC HETEROCYCLENE DERIVATIVES AS PEST CONTROL AGENTS | BAYER AKTIENGESELLSCHAFT (DE) | 2018-08-02 | — | — | WO | disclosed |