Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13384630 | 0.81 | KMT2A (0.35) | KMT2A | |
| SCHEMBL19213325 | 0.80 | KMT2A (0.32) | KMT2A | |
| SCHEMBL19213323 | 0.80 | KMT2A (0.32) | KMT2A | |
| SCHEMBL10109756 | 0.78 | SLC6A3 (0.37) | — | |
| SCHEMBL2732554 | 0.70 | KMT2A (0.56) | KMT2A | |
| SCHEMBL12138136 | 0.69 | KMT2A (0.39) | KMT2A | |
| SCHEMBL21720212 | 0.67 | KMT2A (0.38) | KMT2A | |
| SCHEMBL21720319 | 0.67 | KMT2A (0.38) | KMT2A | |
| SCHEMBL21720478 | 0.67 | KMT2A (0.38) | KMT2A | |
| SCHEMBL18400504 | 0.67 | ALOX5 (0.39) | KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035819-B2 | PPAR agonists and methods of use thereof | THE SALK INSTITUTE FOR BIOLOGICAL STUDIES (US) | 2018-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035819-B2 | PPAR agonists and methods of use thereof | PPARD, PPARG, PPARA | KMT2A 3234/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.