Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BRD4 | O60885 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.44 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.43 |
| ▸ | HPGD | P15428 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.43 |
| ▸ | MRGPRX4 | Q96LA9 | 2/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.42 |
| ▸ | NPC1 | O15118 | 2/20 | 0.42 |
| ▸ | RAB9A | P51151 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | THRB | P10828 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | PTGER1 | P34995 | 2/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1578341 | 0.91 | BRD4 (0.48) | BRD4SMPD1NOTUMALDH1A1HPGD | |
| SCHEMBL1578001 | 0.87 | MAPT (0.56) | BRD4NOTUMALDH1A1KDM4EMAPT | |
| SCHEMBL1578000 | 0.86 | HPGD (0.52) | BRD4SMPD1ALDH1A1HPGDKDM4E | |
| Hydroxyamine SCHEMBL1578310 | 0.84 | MAPT (0.53) | BRD4NOTUMALDH1A1KDM4EMAPT | |
| SCHEMBL2945372 | 0.83 | BRD4 (0.70) | BRD4NOTUMALDH1A1KDM4EMRGPRX4 | |
| SCHEMBL1577761 | 0.83 | RAB9A (0.56) | ALDH1A1HPGDKDM4EHSD17B10NPSR1 | |
| SCHEMBL1578321 | 0.81 | ALDH1A1 (0.47) | SMPD1ALDH1A1HPGDKDM4EHSD17B10 | |
| SCHEMBL12939033 | 0.81 | MAPT (0.56) | BRD4ALDH1A1KDM4EMAPTNPC1 | |
| SCHEMBL12939031 | 0.79 | HPGD (0.51) | BRD4SMPD1ALDH1A1HPGDKDM4E | |
| SCHEMBL20427873 | 0.78 | CYP2C9 (0.41) | BRD4NOTUMALDH1A1HPGDKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10035792-B2 | Resorcinol derivative as HSP90 inhibitor | CHIA TAI TIANQING PHARMACEUTICAL GROUP CO., LTD. (CN) | 2018-07-31 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10035792-B2 | Resorcinol derivative as HSP90 inhibitor | HSP90AB1, HSP90AA1, HSP90AB2P | BRD4 1870/4885SMPD1 4198/4885NOTUM 3076/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.