Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.81 |
| ▸ | RAB9A | P51151 | 9/20 | 0.81 |
| ▸ | RXFP1 | Q9HBX9 | 3/20 | 0.65 |
| ▸ | MEN1 | O00255 | 3/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.65 |
| ▸ | MIF | P14174 | 1/20 | 0.65 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.65 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.65 |
| ▸ | MAOB | P27338 | 4/20 | 0.62 |
| ▸ | POLB | P06746 | 3/20 | 0.61 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | GLA | P06280 | 3/20 | 0.61 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.61 |
| ▸ | GAA | P10253 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 2/20 | 0.61 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | CASP1 | P29466 | 1/20 | 0.61 |
| ▸ | CASP7 | P55210 | 1/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.61 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24446173 | 0.88 | NPC1 (0.72) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL18535684 | 0.85 | NPC1 (0.60) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL7123290 | 0.84 | NPC1 (0.74) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL7116819 | 0.84 | NPC1 (0.83) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL2303012 | 0.81 | NPC1 (0.67) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL20288536 | 0.81 | NPC1 (0.79) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL13486910 | 0.79 | NPC1 (0.71) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL949458 | 0.79 | MIF (1.00) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL29402681 | 0.79 | MIF (1.00) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL9607851 | 0.79 | NPC1 (0.67) | NPC1RAB9ARXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2957618-B1 | LIQUID CRYSTALLINE MEDIUM | MERCK PATENT GMBH (DE) | 2018-08-01 | — | — | EP | disclosed |