Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 7/20 | 0.74 |
| ▸ | RAB9A | P51151 | 7/20 | 0.74 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.68 |
| ▸ | MEN1 | O00255 | 2/20 | 0.68 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.68 |
| ▸ | MIF | P14174 | 1/20 | 0.68 |
| ▸ | SIRT3 | Q9NTG7 | 1/20 | 0.68 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.68 |
| ▸ | MAOB | P27338 | 4/20 | 0.68 |
| ▸ | GLA | P06280 | 3/20 | 0.64 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.64 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.64 |
| ▸ | GAA | P10253 | 2/20 | 0.64 |
| ▸ | HPGD | P15428 | 2/20 | 0.64 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.64 |
| ▸ | POLB | P06746 | 2/20 | 0.64 |
| ▸ | TP53 | P04637 | 1/20 | 0.64 |
| ▸ | CASP1 | P29466 | 1/20 | 0.64 |
| ▸ | CASP7 | P55210 | 1/20 | 0.64 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.64 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116819 | 0.89 | NPC1 (0.83) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL7114353 | 0.88 | MIF (0.60) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL18535597 | 0.87 | MAOB (0.62) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL23713498 | 0.85 | RAB9A (0.56) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL24046282 | 0.85 | MAOB (0.69) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL6686431 | 0.84 | MAOB (0.59) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL20428199 | 0.84 | NPC1 (0.81) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL23713540 | 0.83 | NPC1 (0.54) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL6939176 | 0.83 | NPC1 (0.65) | NPC1RAB9ARXFP1MEN1KMT2A | |
| SCHEMBL10453916 | 0.82 | MAOB (0.80) | NPC1RAB9ARXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003504327-A | — | — | 2003-02-04 | — | — | JP | claimed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | claimed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | claimed |
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |
| EP-1223928-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | Prendergast, Patrick Thomas (IE) | 2002-07-24 | — | — | EP | disclosed |
| WO-2001003681-A2 | USE OF FLAVONES, COUMARINS AND RELATED COMPOUNDS TO TREAT INFECTIONS | PRENDERGAST PATRICK T (IE) | 2001-01-18 | — | — | WO | disclosed |