Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 3/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.39 |
| ▸ | MAPT | P10636 | 7/20 | 0.37 |
| ▸ | LMNA | P02545 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.37 |
| ▸ | HTT | P42858 | 2/20 | 0.37 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.37 |
| ▸ | USP2 | O75604 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | CES1 | P23141 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | GFER | P55789 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | GSK3B | P49841 | 1/20 | 0.33 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.33 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1263095 | 0.67 | ALDH1A1 (0.60) | MAOBALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL8856053 | 0.65 | SLC2A1 (0.58) | MAOBALDH1A1L3MBTL1MAPTTP53 | |
| SCHEMBL24198288 | 0.65 | ALDH1A1 (0.39) | MAOBALDH1A1L3MBTL1MAPTTP53 | |
| SCHEMBL25904709 | 0.65 | S100B (0.39) | MAOBALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL11304575 | 0.63 | MAOB (0.47) | MAOBALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL20420743 | 0.63 | ALDH1A1 (0.59) | ALDH1A1L3MBTL1MAPTLMNATP53 | |
| SCHEMBL11693350 | 0.63 | MAOB (0.47) | MAOBALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL21628199 | 0.63 | MAOB (0.47) | MAOBALDH1A1L3MBTL1MAPTLMNA | |
| SCHEMBL114319 | 0.62 | CA1 (0.61) | ALDH1A1MAPTTP53MAPK1TDP1 | |
| SCHEMBL28043306 | 0.62 | ALDH1A1 (0.40) | MAOBALDH1A1L3MBTL1MAPTTP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354648-A1 | 4-SUBSTITUED COUMARIN DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | Guizhou Bailing Group Pharmaceutical Co., Ltd. (CN) | 2018-08-01 | — | — | EP | disclosed |