Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 4/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.48 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.45 |
| ▸ | HTT | P42858 | 2/20 | 0.45 |
| ▸ | RAB9A | P51151 | 5/20 | 0.44 |
| ▸ | NPC1 | O15118 | 3/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HPGD | P15428 | 7/20 | 0.44 |
| ▸ | MAPT | P10636 | 6/20 | 0.44 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.44 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.44 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20428342 | 0.94 | L3MBTL1 (0.51) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20420798 | 0.94 | L3MBTL1 (0.53) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20420732 | 0.94 | L3MBTL1 (0.53) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20428291 | 0.94 | L3MBTL1 (0.53) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20428309 | 0.92 | ALDH1A1 (0.47) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20428345 | 0.92 | SMN1; SMN2 (0.47) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20428329 | 0.91 | ALDH1A1 (0.44) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL28952542 | 0.90 | ALDH1A1 (0.48) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20428308 | 0.90 | ALDH1A1 (0.45) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 | |
| SCHEMBL20428300 | 0.90 | HTT (0.47) | ALDH1A1KDM4ENPSR1LMNAL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3354648-A1 | 4-SUBSTITUED COUMARIN DERIVATIVE, AND PREPARATION METHOD AND USE THEREOF | Guizhou Bailing Group Pharmaceutical Co., Ltd. (CN) | 2018-08-01 | — | — | EP | disclosed |