Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HMGCR | P04035 | 1/20 | 0.32 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.32 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8197662 | 0.79 | ACLY (0.39) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL13829316 | 0.78 | TSHR (0.37) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL18125738 | 0.77 | — | — | |
| SCHEMBL4202415 | 0.74 | — | — | |
| SCHEMBL5695775 | 0.74 | — | — | |
| SCHEMBL553054 | 0.73 | HMGCR (0.36) | HMGCRCHRM1TBXA2RADRA1ACYP2D6 | |
| SCHEMBL10362142 | 0.72 | — | — | |
| SCHEMBL1691041 | 0.72 | — | — | |
| SCHEMBL25007292 | 0.69 | FAAH (0.42) | — | |
| Potassium Ion SCHEMBL7352758 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |