Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H2 | P55055 | 2/20 | 0.36 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.36 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16660846 | 0.85 | DGAT1 (0.39) | NR1H2NR1H3MALT1 | |
| SCHEMBL20428542 | 0.85 | NR1H2 (0.39) | NR1H2NR1H3MALT1 | |
| SCHEMBL16661014 | 0.69 | DGAT1 (0.41) | NR1H2NR1H3MALT1 | |
| SCHEMBL16660852 | 0.64 | DGAT1 (0.50) | NR1H2NR1H3 | |
| SCHEMBL20428573 | 0.63 | MEN1 (0.36) | — | |
| SCHEMBL16660926 | 0.63 | DGAT1 (0.49) | NR1H2NR1H3 | |
| SCHEMBL18541120 | 0.63 | DGAT1 (0.40) | NR1H2NR1H3 | |
| SCHEMBL16660884 | 0.62 | NR1H3 (0.64) | NR1H2NR1H3 | |
| SCHEMBL16660874 | 0.62 | NR1H3 (0.64) | NR1H2NR1H3 | |
| SCHEMBL16660960 | 0.62 | DGAT1 (0.38) | NR1H2NR1H3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |