Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.32 |
| ▸ | PIK3CD | O00329 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18552799 | 0.75 | RAB9A (0.35) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16408205 | 0.75 | CYP2A6 (0.33) | MEN1KMT2APIK3CD | |
| SCHEMBL18553038 | 0.73 | PTGS2 (0.30) | — | |
| SCHEMBL16660962 | 0.72 | DGAT1 (0.42) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL20428575 | 0.71 | MEN1 (0.37) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL16660943 | 0.69 | DGAT1 (0.49) | MEN1KMT2ADGAT1 | |
| SCHEMBL16661211 | 0.69 | DGAT1 (0.40) | MEN1KMT2AKDM4EALDH1A1HPGD | |
| SCHEMBL18155450 | 0.66 | CYP1A2 (0.32) | — | |
| SCHEMBL19965647 | 0.64 | — | — | |
| SCHEMBL16660965 | 0.64 | DGAT1 (0.41) | MEN1KMT2ALMNADGAT1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |