SCHEMBL20428759

SCHEMBL20428759

CC1(C)OB(c2cccc3nsnc23)OC1(C)C

nearest known ligand 0.43

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 3/20 0.43
KDM4E B2RXH2 3/20 0.43
HSD17B10 Q99714 3/20 0.43
HIF1A Q16665 1/20 0.43
ALDH1A1 P00352 4/20 0.39
POLB P06746 1/20 0.39
TXNRD1 Q16881 1/20 0.38
TXNRD3 Q86VQ6 1/20 0.38
TXNRD2 Q9NNW7 1/20 0.38
USP2 O75604 1/20 0.37
DUSP3 P51452 1/20 0.36
PTPN5 P54829 1/20 0.36
CASP6 P55212 1/20 0.36
PTPN11 Q06124 1/20 0.36
CTDSP1 Q9GZU7 1/20 0.36
LPL P06858 2/20 0.36
LIPG Q9Y5X9 2/20 0.36
MEN1 O00255 2/20 0.34
KMT2A Q03164 2/20 0.34
HPGD P15428 2/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL1274759 0.83 LPL (0.36) LPLLIPG
SCHEMBL2569051 0.79 MAPT (0.37) MAPTKDM4EHSD17B10HIF1AALDH1A1
SCHEMBL26921621 0.78 ALDH1A1 (0.37) MAPTKDM4EHSD17B10HIF1AALDH1A1
SCHEMBL15230780 0.75 MAPT (0.41) MAPTKDM4EHSD17B10ALDH1A1POLB
SCHEMBL14785705 0.75 KMT2A (0.41) MAPTALDH1A1POLBLPLLIPG
SCHEMBL14353426 0.74 LPL (0.34) LPLLIPG
SCHEMBL14376978 0.74 LPL (0.34) LPLLIPG
SCHEMBL19554130 0.74 MEN1 (0.30) MEN1KMT2A
SCHEMBL20479422 0.73 JAK2 (0.34) LPLLIPG
SCHEMBL2334221 0.73 LPL (0.35) LPLLIPG

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 29 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115487866-B Covalent organic framework material coupling nano metal catalyst and preparation method thereof 浙江大学 2024-05-14 CN claimed
CN-113061333-B Low-dielectric thermoplastic polyurethane composite material and preparation method and application thereof 万华化学集团股份有限公司 2022-08-05 CN claimed
CN-113061333-A Low-dielectric thermoplastic polyurethane composite material and preparation method and application thereof 万华化学集团股份有限公司 2021-07-02 CN claimed
CN-110523354-B Preparation method of microreactor containing immobilized catalyst 浙江大学 2021-01-19 CN claimed
CN-110776506-A Benzothiadiazole bridged spiroaryl electroluminescent material and preparation method and application thereof 沈阳化工大学 2020-02-11 CN claimed
CN-118420521-A Terpyridyl zinc complex and application thereof 中南大学 2024-08-02 CN disclosed
CN-115487866-B Covalent organic framework material coupling nano metal catalyst and preparation method thereof 浙江大学 2024-05-14 CN disclosed
CN-117594772-A Graphene microsphere-based electrode material and preparation method thereof 上海博超纳烯新能源科技有限公司 2024-02-23 CN disclosed
CN-117186366-A Quinoid-donor-acceptor conjugated polymer containing mixed side chain, preparation and application 贵州大学 2023-12-08 CN disclosed
EP-3976608-B1 THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES INC (US) 2023-11-08 EP disclosed
CN-116854894-A Covalent organic framework material with three-dimensional structure and synthesis method thereof 河南科技大学 2023-10-10 CN disclosed
CN-116854894-A Covalent organic framework material with three-dimensional structure and synthesis method thereof 河南科技大学 2023-10-10 CN disclosed
CN-108368142-B Method for producing aromatic compound and palladium complex 住友化学株式会社 2021-02-19 CN disclosed
CN-110523354-B Preparation method of microreactor containing immobilized catalyst 浙江大学 2021-01-19 CN disclosed
WO-2020243459-A1 THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2020-12-03 WO disclosed
WO-2020243459-A1 THIADIAZOLYL DERIVATIVES AS DNA POLYMERASE THETA INHIBITORS IDEAYA BIOSCIENCES, INC. (US) 2020-12-03 WO disclosed
CN-110487735-B Gas sensor based on covalent organic framework material and preparation method thereof 浙江大学 2020-10-16 CN disclosed
CN-110776506-A Benzothiadiazole bridged spiroaryl electroluminescent material and preparation method and application thereof 沈阳化工大学 2020-02-11 CN disclosed
EP-2562197-B1 COPOLYMER COMPRISING ANTHRACENE AND BENZOSELENADIAZOLE, PREPARING METHOD AND USES THEREOF OCEANS KING LIGHTING SCI & TEC (CN) 2018-08-01 EP disclosed
CN-102598341-B Photoelectric conversion element SUMITOMO CHEMICAL CO 2015-02-11 CN disclosed