Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DCUN1D1 | Q96GG9 | 9/20 | 0.48 |
| ▸ | ALPL | P05186 | 3/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.41 |
| ▸ | RAB9A | P51151 | 3/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | ATM | Q13315 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.40 |
| ▸ | ALPG | P10696 | 1/20 | 0.36 |
| ▸ | GRK6 | P43250 | 2/20 | 0.35 |
| ▸ | DCUN1D2 | Q6PH85 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16661263 | 0.82 | DCUN1D1 (0.48) | DCUN1D1ALPLNPC1RAB9AKDM4E | |
| SCHEMBL8158453 | 0.68 | DCUN1D1 (0.74) | DCUN1D1ALPLNPC1RAB9AKDM4E | |
| SCHEMBL16661004 | 0.68 | DCUN1D1 (0.48) | DCUN1D1ALPLNPC1RAB9AKDM4E | |
| SCHEMBL25957505 | 0.67 | DCUN1D1 (0.66) | DCUN1D1ALPLNPC1RAB9AKDM4E | |
| SCHEMBL6269096 | 0.67 | IDO1 (0.43) | — | |
| SCHEMBL7847296 | 0.65 | NISCH (0.40) | NPC1RAB9AKDM4EMEN1KMT2A | |
| SCHEMBL16661200 | 0.64 | DCUN1D1 (0.42) | DCUN1D1ALPLNPC1RAB9AKDM4E | |
| SCHEMBL16661201 | 0.64 | DCUN1D1 (0.57) | DCUN1D1ALPLNPC1RAB9AKDM4E | |
| SCHEMBL1528139 | 0.64 | ALPL (1.00) | DCUN1D1ALPLNPC1RAB9ALMNA | |
| SCHEMBL7635074 | 0.63 | DCUN1D1 (0.71) | DCUN1D1ALPLNPC1RAB9AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2862856-B1 | IMIDAZOLE AND TRIAZOLE COMPOUNDS AS DGAT-1 INHIBITORS | MITSUBISHI TANABE PHARMA CORP (JP) | 2018-08-01 | — | — | EP | disclosed |