Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NISCH | Q9Y2I1 | 2/20 | 0.40 |
| ▸ | MTOR | P42345 | 1/20 | 0.40 |
| ▸ | ADK | P55263 | 1/20 | 0.40 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.38 |
| ▸ | TYRO3 | Q06418 | 1/20 | 0.38 |
| ▸ | DYRK1B | Q9Y463 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | MC4R | P32245 | 1/20 | 0.36 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.35 |
| ▸ | ADRA2C | P18825 | 2/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 2/20 | 0.35 |
| ▸ | ADRA1D | P25100 | 1/20 | 0.35 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | ADRA2B | P18089 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3631532 | 0.81 | RAB9A (0.50) | NISCHMTORADKCSNK1A1TYRO3 | |
| SCHEMBL2455067 | 0.79 | NISCH (0.46) | NISCHMTORADKCSNK1A1TYRO3 | |
| SCHEMBL1688524 | 0.79 | NISCH (0.49) | NISCHMTORADKNPC1RAB9A | |
| SCHEMBL3629052 | 0.79 | MC4R (0.49) | NISCHMTORADKCSNK1A1TYRO3 | |
| SCHEMBL1458606 | 0.76 | NISCH (0.53) | NISCHMTORADKCSNK1A1TYRO3 | |
| SCHEMBL18519805 | 0.75 | ALDH1A1 (0.47) | NISCHMTORADKCSNK1A1TYRO3 | |
| SCHEMBL6269096 | 0.73 | IDO1 (0.43) | ADRA2AADRA2BIDO1 | |
| SCHEMBL8542466 | 0.73 | ALDH1A1 (0.49) | NISCHMTORADKCSNK1A1TYRO3 | |
| SCHEMBL18520272 | 0.72 | KDM4E (0.47) | CSNK1A1TYRO3DYRK1BALDH1A1KDM4E | |
| SCHEMBL6003163 | 0.71 | ABL1 (0.53) | NPC1RAB9AABL1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071684-A4 | IMIDAZO 1,2-a]PYRIDINES AS PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | AUSTRALIAN NUCLEAR SCIENCE TEC (AU) | 2001-10-04 | — | — | EP | disclosed |
| EP-1071684-A1 | IMIDAZO 1,2-a]PYRIDINES AS PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999051594-A1 | IMIDAZO[1,2-a]PYRIDINES AS PERIPHERAL BENZODIAZEPINE RECEPTOR BINDING AGENTS | AUSTRALIAN NUCLEAR SCIENCE & TECHNOLOGY ORGANISATION (AU) | 1999-10-14 | — | — | WO | disclosed |