SCHEMBL2042928

SCHEMBL2042928

O=[N+]([O-])c1n[c]c[nH]1

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16408536 0.65
SCHEMBL4262425 0.62
SCHEMBL2442590 0.60
Azomycin SCHEMBL3804535 0.60 MEN1 (0.46)
Azomycin SCHEMBL10049 0.60
Azomycin SCHEMBL4349167 0.59
Azomycin SCHEMBL29116196 0.59
SCHEMBL64072 0.59 CYP3A4 (0.33)
Azomycin SCHEMBL29413971 0.59 MEN1 (0.44)
Azomycin SCHEMBL31554956 0.59

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 27 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180185522-A1 CONTRAST AGENT FOR IMAGING HYPOXIA OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2018-07-05 US claimed
WO-2016092325-A1 CONTRAST AGENT FOR IMAGING HYPOXIA ISIS INNOVATION LIMITED (GB) 2016-06-16 WO claimed
EP-1148878-A4 1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AS RADIODIGANOSTIC AGENTS AND THEIR USE IN DETERMINING HYPOXIA AND RADIORESISTANCE OF TUMORS FOX CHASE CANCER CT (US) 2003-04-02 EP claimed
EP-1148878-A1 1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AS RADIODIGANOSTIC AGENTS AND THEIR USE IN DETERMINING HYPOXIA AND RADIORESISTANCE OF TUMORS FOX CHASE CANCER CENTER (US) 2001-10-31 EP claimed
WO-2000043004-A1 1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AS RADIODIGANOSTIC AGENTS AND THEIR USE IN DETERMINING HYPOXIA AND RADIORESISTANCE OF TUMORS FOX CHASE CANCER CENTER (US) 2000-07-27 WO claimed
WO-1994006798-A1 NOVEL BIOREDUCTIVE COMPOUNDS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-03-31 WO claimed
CN-109651350-B Heterocyclic substituted 1,3,4-oxa (thia) diazoles compound and preparation method and application thereof 贵州大学 2022-05-24 CN disclosed
EP-2816036-B1 PRODRUG USING NITROIMIDAZOLE UNIV TSUKUBA (JP) 2019-04-17 EP disclosed
US-20180185522-A1 CONTRAST AGENT FOR IMAGING HYPOXIA OXFORD UNIVERSITY INNOVATION LIMITED (GB) 2018-07-05 US disclosed
US-9655975-B2 Prodrug using nitroimidazole UNIVERSITY OF TSUKUBA (JP) 2017-05-23 US disclosed
WO-2016092325-A1 CONTRAST AGENT FOR IMAGING HYPOXIA ISIS INNOVATION LIMITED (GB) 2016-06-16 WO disclosed
US-20140378673-A1 PRODRUG USING NITROIMIDAZOLE UNIVERSITY OF TSUKUBA (JP) 2014-12-25 US disclosed
EP-2816036-A1 PRODRUG USING NITROIMIDAZOLE University of Tsukuba (JP) 2014-12-24 EP disclosed
EP-1148878-A1 1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AS RADIODIGANOSTIC AGENTS AND THEIR USE IN DETERMINING HYPOXIA AND RADIORESISTANCE OF TUMORS FOX CHASE CANCER CENTER (US) 2001-10-31 EP disclosed
WO-2000043004-A1 1,4,8,11-TETRAAZACYCLOTETRADECANE DERIVATIVES AS RADIODIGANOSTIC AGENTS AND THEIR USE IN DETERMINING HYPOXIA AND RADIORESISTANCE OF TUMORS FOX CHASE CANCER CENTER (US) 2000-07-27 WO disclosed
EP-0629617-B1 Heteroatom-bearing ligands and metal complexes thereof BRACCO INT BV (NL) 1998-04-29 EP disclosed
US-5665329-A Heteroatom-bearing ligands and metal complexes thereof BRACCO INTERNATIONAL B.V. 1997-09-09 US disclosed
EP-0629617-A1 Heteroatom-bearing ligands and metal complexes thereof BRACCO International B.V. (NL) 1994-12-21 EP disclosed
WO-1994006798-A1 NOVEL BIOREDUCTIVE COMPOUNDS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-03-31 WO disclosed
WO-1994006798-A1 NOVEL BIOREDUCTIVE COMPOUNDS BRITISH TECHNOLOGY GROUP LIMITED (GB) 1994-03-31 WO disclosed