Known targets — ChEMBL curated mechanism
AGTR1DHFRGABBR1GABBR2GABRA1GABRA2GABRA3GABRA4GABRA5GABRA6GABRB1GABRB2GABRB3GABRDGABREGABRG1GABRG2GABRG3GABRPGABRQGARTNR3C2PBP2XPTGS1PTGS2VKORC1blablaT-3blaT-4blaT-5blaT-6dacAdacBdacCfolAftsImrcAmrcBmrdApbp1apbp1bpbp2apbp2bpbp3polthyA
The experimentally established mechanism targets of Azomycin. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Azomycin SCHEMBL10049 | 0.98 | — | — | |
| Azomycin SCHEMBL3804535 | 0.98 | MEN1 (0.46) | — | |
| Azomycin SCHEMBL31554956 | 0.95 | — | — | |
| Azomycin SCHEMBL4553768 | 0.95 | — | — | |
| Azomycin SCHEMBL29413971 | 0.95 | MEN1 (0.44) | — | |
| Azomycin SCHEMBL8400797 | 0.95 | — | — | |
| Azomycin SCHEMBL4349164 | 0.95 | — | — | |
| Azomycin SCHEMBL4231042 | 0.95 | — | — | |
| Azomycin SCHEMBL29116196 | 0.95 | — | — | |
| Azomycin SCHEMBL28751634 | 0.95 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1391456-B1 | 2-IMINOIMIDAZOLE DERIVATIVES | EISAI R&D MAN CO LTD (JP) | 2009-07-22 | — | — | EP | disclosed |
| US-7304083-B2 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2007-12-04 | — | — | US | disclosed |
| US-20050004197-A1 | 2-iminoimidazole derivatives (2) | EISAI R&D MANAGEMENT CO., LTD. (JP) | 2005-01-06 | — | — | US | disclosed |
| EP-1391456-A1 | 2-IMINOIMIDAZOLE DERIVATIVE (2) | Eisai Co., Ltd. (JP) | 2004-02-25 | — | — | EP | disclosed |