Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 2/20 | 0.48 |
| ▸ | SLC29A1 | Q99808 | 5/20 | 0.47 |
| ▸ | PI4KA | P42356 | 1/20 | 0.45 |
| ▸ | PI4K2B | Q8TCG2 | 1/20 | 0.45 |
| ▸ | PI4K2A | Q9BTU6 | 1/20 | 0.45 |
| ▸ | PI4KB | Q9UBF8 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20435001 | 1.00 | ADORA3 (0.48) | ADORA3SLC29A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL26292114 | 0.92 | ADORA3 (0.45) | ADORA3SLC29A1 | |
| SCHEMBL20435013 | 0.92 | ADORA3 (0.45) | ADORA3SLC29A1 | |
| SCHEMBL20435000 | 0.92 | ADORA3 (0.45) | ADORA3SLC29A1 | |
| SCHEMBL24505768 | 0.84 | ADORA2B (0.49) | ADORA3SLC29A1 | |
| SCHEMBL20434988 | 0.83 | PI4KA (0.64) | ADORA3SLC29A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20434974 | 0.83 | PI4KA (0.64) | ADORA3SLC29A1PI4KAPI4K2BPI4K2A | |
| SCHEMBL20434987 | 0.79 | ADORA3 (0.62) | ADORA3SLC29A1 | |
| SCHEMBL26292120 | 0.79 | ADORA3 (0.62) | ADORA3SLC29A1 | |
| SCHEMBL20435018 | 0.79 | ADORA3 (0.62) | ADORA3SLC29A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ACADEMIA SINICA (TW) | 2023-09-12 | — | — | US | disclosed |
| EP-3573996-B1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ACADEMIA SINICA (TW) | 2022-06-15 | — | — | EP | disclosed |
| WO-2018140734-A1 | COMPOUND WITH ANALGESIC EFFECT FOR USE IN PREVENTION AND TREATMENT OF PAIN | ACADEMIA SINICA (TW) | 2018-08-02 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11753432-B2 | Compound with analgesic effect for use in prevention and treatment of pain | ADORA2B, ADORA1, ADORA3 | ADORA3 3/4885SLC29A1 347/4885PI4KA 3007/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.