SCHEMBL20436757

SCHEMBL20436757

CC(=O)N(C(C)=O)C1=CC[C@@H](c2ccc(Cl)c(C)c2)c2ccccc21

nearest known ligand 0.38

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
STING1 Q86WV6 1/20 0.38
SLC6A4 P31645 10/20 0.37
SLC6A2 P23975 10/20 0.37
SLC6A3 Q01959 9/20 0.37
MEN1 O00255 1/20 0.36
ALDH1A1 P00352 1/20 0.36
MAPT P10636 1/20 0.36
KMT2A Q03164 1/20 0.36
KCNH2 Q12809 1/20 0.34
MAOB P27338 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13823807 1.00 STING1 (0.38) STING1SLC6A4SLC6A2SLC6A3MEN1
SCHEMBL10071232 0.91 SLC6A4 (0.37) SLC6A4SLC6A2SLC6A3MEN1ALDH1A1
SCHEMBL10041962 0.91 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3
SCHEMBL10075506 0.91 SLC6A4 (0.46) SLC6A4SLC6A2SLC6A3
SCHEMBL10071233 0.81 SLC6A2 (0.37) STING1SLC6A4SLC6A2SLC6A3MEN1
SCHEMBL10050930 0.81 SLC6A2 (0.37) STING1SLC6A4SLC6A2SLC6A3MEN1
SCHEMBL20340496 0.81 SLC6A2 (0.37) STING1SLC6A4SLC6A2SLC6A3MEN1
SCHEMBL10070677 0.71 SMN1; SMN2 (0.40) SLC6A4SLC6A2SLC6A3MEN1ALDH1A1
SCHEMBL20341083 0.71 SLC6A2 (0.44) SLC6A4SLC6A2SLC6A3MEN1MAPT
SCHEMBL29757853 0.71 SLC6A2 (0.44) SLC6A4SLC6A2SLC6A3MEN1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20180215702-A1 ENAMIDE PROCESS SUNOVION PHARMACEUTICALS INC. 2018-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180215702-A1 ENAMIDE PROCESS ENO1, ENY2, ALKBH2 STING1 1776/4885SLC6A4 3378/4885SLC6A2 1680/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.