⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20436778 | 1.00 | — | — | |
| SCHEMBL24282821 | 0.91 | TAS1R3 (0.32) | — | |
| SCHEMBL18736497 | 0.85 | — | — | |
| SCHEMBL12180002 | 0.82 | — | — | |
| SCHEMBL22276417 | 0.79 | — | — | |
| SCHEMBL87230 | 0.78 | — | — | |
| SCHEMBL20436769 | 0.77 | CA12 (0.37) | — | |
| SCHEMBL12912878 | 0.76 | — | — | |
| SCHEMBL20442214 | 0.75 | — | — | |
| SCHEMBL26454190 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4306538-A2 | PEPTIDE OLIGONUCLEOTIDE CONJUGATES | Sarepta Therapeutics, Inc. (US) | 2024-01-17 | — | — | EP | disclosed |
| US-20230310625-A1 | Peptide Oligonucleotide Conjugates | JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT | 2023-10-05 | — | — | US | disclosed |
| US-11672871-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-11672871-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2023-06-13 | — | — | US | disclosed |
| US-10675356-B2 | Peptide oligonucleotide conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2020-06-09 | — | — | US | disclosed |
| US-20180214567-A1 | Peptide Oligonucleotide Conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2018-08-02 | — | — | US | disclosed |
| US-20180214567-A1 | Peptide Oligonucleotide Conjugates | SAREPTA THERAPEUTICS, INC. (US) | 2018-08-02 | — | — | US | disclosed |