SCHEMBL20436769

SCHEMBL20436769

CC(C)c1c(F)c(F)c(SCCSc2c(F)c(F)c(C(C)C)c(F)c2F)c(F)c1F

nearest known ligand 0.37

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CA12 O43570 3/20 0.37
CA1 P00915 3/20 0.37
CA2 P00918 3/20 0.37
CA7 P43166 3/20 0.37
CA13 Q8N1Q1 3/20 0.37
CA9 Q16790 2/20 0.37
SMN1; SMN2 Q16637 1/20 0.36
CA3 P07451 1/20 0.33
CA4 P22748 1/20 0.33
CA6 P23280 1/20 0.33
CA5A P35218 1/20 0.33
CA14 Q9ULX7 1/20 0.33
CA5B Q9Y2D0 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL17718485 0.87 SMN1; SMN2 (0.56) CA12CA1CA2CA7CA13
SCHEMBL17718486 0.81 CA12 (0.55) CA12CA1CA2CA7CA13
SCHEMBL20436778 0.77
SCHEMBL20436768 0.77
SCHEMBL20436774 0.77 CA12 (0.42) CA12CA1CA2CA7CA13
SCHEMBL12180002 0.76
SCHEMBL13778590 0.73 CA12 (0.54) CA12CA1CA2CA7CA13
SCHEMBL87230 0.73
SCHEMBL18257672 0.72 CA12 (0.41) CA12CA1CA2CA7CA13
SCHEMBL12912878 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20230310625-A1 Peptide Oligonucleotide Conjugates JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2023-10-05 US disclosed
US-20230310625-A1 Peptide Oligonucleotide Conjugates JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2023-10-05 US disclosed
US-11672871-B2 Peptide oligonucleotide conjugates SAREPTA THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
US-11672871-B2 Peptide oligonucleotide conjugates SAREPTA THERAPEUTICS, INC. (US) 2023-06-13 US disclosed
US-20200254109-A1 Peptide Oligonucleotide Conjugates JPMORGAN CHASE BANK, N.A. AS ADMINISTRATIVE AGENT 2020-08-13 US disclosed
US-10675356-B2 Peptide oligonucleotide conjugates SAREPTA THERAPEUTICS, INC. (US) 2020-06-09 US disclosed
US-20180214567-A1 Peptide Oligonucleotide Conjugates SAREPTA THERAPEUTICS, INC. (US) 2018-08-02 US disclosed
US-20180214567-A1 Peptide Oligonucleotide Conjugates SAREPTA THERAPEUTICS, INC. (US) 2018-08-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20180214567-A1 Peptide Oligonucleotide Conjugates MYOF, MUSK, MTPN CA12 2063/4885CA1 3676/4885CA2 4261/4885
US-20230310625-A1 Peptide Oligonucleotide Conjugates MYOF, MUSK, MTPN CA12 2063/4885CA1 3676/4885CA2 4261/4885
US-10675356-B2 Peptide oligonucleotide conjugates MYOF, MUSK, MTPN CA12 2063/4885CA1 3676/4885CA2 4261/4885
US-20200254109-A1 Peptide Oligonucleotide Conjugates MYOF, MUSK, MTPN CA12 2063/4885CA1 3676/4885CA2 4261/4885
US-11672871-B2 Peptide oligonucleotide conjugates MYOF, MUSK, MTPN CA12 2063/4885CA1 3676/4885CA2 4261/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.