Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | ADORA3 | P0DMS8 | 3/20 | 0.45 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.45 |
| ▸ | ADORA1 | P30542 | 3/20 | 0.45 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.45 |
| ▸ | CASP3 | P42574 | 1/20 | 0.43 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.43 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | ACP1 | P24666 | 3/20 | 0.42 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11978705 | 0.91 | L3MBTL1 (0.47) | L3MBTL1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL22063718 | 0.90 | L3MBTL1 (0.58) | L3MBTL1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL25823034 | 0.84 | CASP3 (0.54) | L3MBTL1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL20026605 | 0.81 | CYP2D6 (0.40) | L3MBTL1TDP1POLBCASP3SENP7 | |
| SCHEMBL20026641 | 0.80 | L3MBTL1 (0.51) | L3MBTL1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL22754758 | 0.79 | TDP1 (0.51) | L3MBTL1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL20805721 | 0.79 | L3MBTL1 (0.56) | L3MBTL1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL19295107 | 0.79 | TDP1 (0.51) | L3MBTL1TDP1ADORA3ADORA2AADORA1 | |
| SCHEMBL371042 | 0.78 | L3MBTL1 (0.74) | L3MBTL1ADORA3ADORA2AADORA1POLB | |
| SCHEMBL22754878 | 0.78 | CA1 (0.47) | L3MBTL1TDP1ADORA3ADORA2AADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3160954-B1 | MATERIALS FOR ORGANIC ELECTROLUMINESCENT DEVICES | MERCK PATENT GMBH (DE) | 2020-09-23 | — | — | EP | disclosed |
| WO-2018138039-A1 | CARBAZOLE DERIVATIVES | MERCK PATENT GMBH (DE) | 2018-08-02 | — | — | WO | disclosed |