SCHEMBL2043782

SCHEMBL2043782

CO/N=C(\C/C(C)=N/OC)Cc1ccccc1

nearest known ligand 0.43

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
MAPT P10636 4/20 0.43
ALDH1A1 P00352 10/20 0.42
SMN1; SMN2 Q16637 4/20 0.40
LMNA P02545 4/20 0.40
L3MBTL1 Q9Y468 3/20 0.40
KMT2A Q03164 2/20 0.40
GAA P10253 1/20 0.40
HTT P42858 1/20 0.40
KDM4E B2RXH2 4/20 0.40
RAB9A P51151 2/20 0.39
NPC1 O15118 1/20 0.39
MEN1 O00255 1/20 0.39
THRB P10828 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
PLAU P00749 1/20 0.37
ELANE P08246 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2043783 1.00 MAPT (0.43) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL18840185 0.85 ALDH1A1 (0.43) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL19433075 0.83 MAPT (0.49) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL18840218 0.83 MAPT (0.49) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL10177918 0.83 MAPT (0.49) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL9899495 0.81 KDM4E (0.45) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL9899496 0.81 KDM4E (0.45) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL2049544 0.80 SMN1; SMN2 (0.41) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL2049548 0.80 SMN1; SMN2 (0.41) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1
SCHEMBL2049447 0.79 ALDH1A1 (0.38) MAPTALDH1A1SMN1; SMN2LMNAL3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed