SCHEMBL2049447

SCHEMBL2049447

CC(CC(Cc1ccccc1)=NO[Si](C)(C)C)=NO[Si](C)(C)C

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KMT2A Q03164 4/20 0.37
LMNA P02545 3/20 0.37
GAA P10253 2/20 0.37
HTT P42858 1/20 0.37
KDM4E B2RXH2 4/20 0.37
MAPT P10636 2/20 0.36
MEN1 O00255 2/20 0.36
XDH P47989 1/20 0.35
NPC1 O15118 1/20 0.33
RAB9A P51151 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2049446 1.00 ALDH1A1 (0.38) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL2044909 0.88 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL2044910 0.88 ALDH1A1 (0.36) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL9899271 0.83 KDM4E (0.42) ALDH1A1SMN1; SMN2L3MBTL1KMT2AGAA
SCHEMBL9899268 0.83 KDM4E (0.42) ALDH1A1SMN1; SMN2L3MBTL1KMT2AGAA
SCHEMBL2043783 0.79 MAPT (0.43) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL2043782 0.79 MAPT (0.43) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA
SCHEMBL2050696 0.77
SCHEMBL2050699 0.77
SCHEMBL2045429 0.76 ALDH1A1 (0.35) ALDH1A1SMN1; SMN2L3MBTL1KMT2ALMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP claimed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US claimed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP claimed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US claimed
EP-2516475-B1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORP (JP) 2020-10-07 EP disclosed
US-8338544-B2 Polymers functionalized with polyoxime compounds and methods for their manufacture BRIDGESTONE CORPORATION (JP) 2012-12-25 US disclosed
EP-2516475-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE Bridgestone Corporation (JP) 2012-10-31 EP disclosed
US-20110152449-A1 POLYMERS FUNCTIONALIZED WITH POLYOXIME COMPOUNDS AND METHODS FOR THEIR MANUFACTURE BRIDGESTONE CORPORATION (JP) 2011-06-23 US disclosed