Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.66 |
| ▸ | LMNA | P02545 | 1/20 | 0.66 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.66 |
| ▸ | CNR1 | P21554 | 1/20 | 0.66 |
| ▸ | ATM | Q13315 | 1/20 | 0.66 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.66 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | MMP1 | P03956 | 2/20 | 0.44 |
| ▸ | MMP2 | P08253 | 1/20 | 0.43 |
| ▸ | MMP9 | P14780 | 1/20 | 0.43 |
| ▸ | MMP12 | P39900 | 1/20 | 0.43 |
| ▸ | CETP | P11597 | 1/20 | 0.43 |
| ▸ | FFAR1 | O14842 | 5/20 | 0.42 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.41 |
| ▸ | CCR8 | P51685 | 1/20 | 0.41 |
| ▸ | PTGES | O14684 | 1/20 | 0.40 |
| ▸ | PPARG | P37231 | 1/20 | 0.39 |
| ▸ | PPARA | Q07869 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16282001 | 1.00 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9670492 | 1.00 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL9670495 | 1.00 | TDP1 (0.66) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10974510 | 0.89 | TDP1 (0.62) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL2127178 | 0.86 | TDP1 (0.67) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL294606 | 0.86 | TDP1 (0.67) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL21820776 | 0.85 | TDP1 (0.74) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL11418777 | 0.84 | TDP1 (0.67) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10976834 | 0.84 | TDP1 (0.64) | TDP1LMNAADRA2ACNR1ATM | |
| SCHEMBL10972736 | 0.84 | TDP1 (0.64) | TDP1LMNAADRA2ACNR1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10271553-B2 | Spot-on active substance formulation | EVERGREEN ANIMAL HEALTH, LLC (US) | 2019-04-30 | — | — | US | disclosed |
| US-20180213791-A1 | Novel Spot-On Active Substance Formulation | EVERGREEN ANIMAL HEALTH, LLC | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180213791-A1 | Novel Spot-On Active Substance Formulation | CHRM3, CHRNG, CHRND | TDP1 4730/4885LMNA 2068/4885ADRA2A 226/4885 |
| US-10271553-B2 | Spot-on active substance formulation | CHRNG, CHRM3, CHRNA10 | TDP1 4793/4885LMNA 1981/4885ADRA2A 197/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.