Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | CA2 | P00918 | 1/20 | 0.46 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.39 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.39 |
| ▸ | KIF11 | P52732 | 1/20 | 0.38 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.37 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.36 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30678520 | 0.91 | ALDH1A1 (0.43) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL48365 | 0.91 | ALDH1A1 (0.43) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| Methylamine SCHEMBL28294592 | 0.85 | ALDH1A1 (0.57) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL580584 | 0.85 | ALDH1A1 (0.63) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL29355273 | 0.85 | ALDH1A1 (0.63) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| Hydrochloric Acid SCHEMBL31147078 | 0.79 | ALDH1A1 (0.57) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| Bromomethane SCHEMBL28461678 | 0.79 | ALDH1A1 (0.57) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| Methyl Alcohol SCHEMBL28457865 | 0.79 | ALDH1A1 (0.65) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL6458088 | 0.79 | TDP1 (0.46) | TDP1ALDH1A1TSHRCA2GABRA1 | |
| SCHEMBL4500149 | 0.79 | ALDH1A1 (0.45) | TDP1ALDH1A1TSHRGRIN2DGRIN3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20190256650-A1 | CATALYTIC CARBONYLATION CATALYSTS AND METHODS | NOVOMER, INC. (US) | 2019-08-22 | — | — | US | disclosed |
| US-20180216107-A1 | OLIGONUCLEOTIDE COMPOSITIONS AND METHODS THEREOF | WAVE LIFE SCIENCES LTD. (SG) | 2018-08-02 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20190256650-A1 | CATALYTIC CARBONYLATION CATALYSTS AND METHODS | CBR3, CBR1, EPHX2 | TDP1 4038/4885ALDH1A1 181/4885TSHR 4642/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.