Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP30 | Q70CQ3 | 4/20 | 0.52 |
| ▸ | DPP4 | P27487 | 1/20 | 0.41 |
| ▸ | RORC | P51449 | 3/20 | 0.40 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.40 |
| ▸ | IDO1 | P14902 | 1/20 | 0.39 |
| ▸ | TDO2 | P48775 | 1/20 | 0.39 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.38 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.38 |
| ▸ | PDE4B | Q07343 | 2/20 | 0.38 |
| ▸ | CACNB4 | O00305 | 1/20 | 0.38 |
| ▸ | CACNA1A | O00555 | 1/20 | 0.38 |
| ▸ | CACNA1G | O43497 | 1/20 | 0.38 |
| ▸ | CACNG3 | O60359 | 1/20 | 0.38 |
| ▸ | CACNA1F | O60840 | 1/20 | 0.38 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.38 |
| ▸ | CACNB3 | P54284 | 1/20 | 0.38 |
| ▸ | CACNA2D1 | P54289 | 1/20 | 0.38 |
| ▸ | CACNG7 | P62955 | 1/20 | 0.38 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20165945 | 0.89 | USP30 (0.43) | USP30DPP4RORCGPR119NR1H2 | |
| SCHEMBL25394031 | 0.87 | GPR119 (0.53) | USP30DPP4GPR119PDE4B | |
| SCHEMBL22817815 | 0.84 | USP30 (0.43) | USP30DPP4RORCGPR119NR1H2 | |
| SCHEMBL20425239 | 0.84 | USP30 (0.57) | USP30RORCGPR119PDE4B | |
| SCHEMBL31401077 | 0.82 | USP30 (0.47) | USP30DPP4GPR119CACNB4CACNA1A | |
| SCHEMBL27105204 | 0.82 | GPR119 (0.47) | USP30DPP4RORCGPR119NR1H2 | |
| SCHEMBL24049588 | 0.81 | USP30 (0.54) | USP30RORCGPR119PDE4BCACNB4 | |
| SCHEMBL22817807 | 0.80 | NR1H2 (0.44) | USP30RORCGPR119NR1H2HDAC1 | |
| SCHEMBL20425147 | 0.80 | ACACB (0.33) | USP30 | |
| SCHEMBL10068009 | 0.80 | CHRM2 (0.50) | USP30DPP4GPR119 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |