SCHEMBL10068009 — predicted protein targets

Predicted protein targets (top 8)

	gene	UniProt	supporting neighbours	confidence
▸	CHRM2	P08172	1/20	0.50

▸	CHRM1	P11229	1/20	0.50

▸	CHRM3	P20309	1/20	0.50

▸	GPR119	Q8TDV5	12/20	0.45

▸	USP30	Q70CQ3	1/20	0.39

▸	DPP4	P27487	1/20	0.39

▸	PREP	P48147	2/20	0.39

▸	HSD11B1	P28845	1/20	0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compound	similarity	top predicted	shared targets
SCHEMBL12094647	0.84	CHRM2 (0.48)	CHRM2CHRM1CHRM3GPR119DPP4
SCHEMBL25394031	0.81	GPR119 (0.53)	GPR119USP30DPP4
SCHEMBL1029432	0.81	CHRM2 (0.47)	CHRM2CHRM1CHRM3GPR119PREP
SCHEMBL1029431	0.81	CHRM2 (0.47)	CHRM2CHRM1CHRM3GPR119PREP
SCHEMBL20439309	0.80	USP30 (0.52)	GPR119USP30DPP4
SCHEMBL903887	0.80	GPR119 (0.53)	GPR119
SCHEMBL10068008	0.79	GPR119 (0.41)	CHRM2CHRM1CHRM3GPR119HSD11B1
SCHEMBL14873168	0.79	GPR119 (0.51)	CHRM2CHRM1CHRM3GPR119
SCHEMBL15058621	0.78	GPR119 (0.48)	CHRM2CHRM1CHRM3GPR119PREP
SCHEMBL15058619	0.78	GPR119 (0.48)	CHRM2CHRM1CHRM3GPR119PREP

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

Patent	Title	Assignee	Published	Priority	Filing	Country	Status
WO-2012041158-A1	TRICYCLIC COMPOUND, PREPARATION METHOD AND PHARMACEUTICAL USE THEREOF	上海恒瑞医药有限公司 (CN)	2012-04-05	—	—	WO	disclosed