Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 5/20 | 0.40 |
| ▸ | HTT | P42858 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | MITF | O75030 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | CNR2 | P34972 | 1/20 | 0.36 |
| ▸ | GPR35 | Q9HC97 | 1/20 | 0.36 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.36 |
| ▸ | XBP1 | P17861 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.36 |
| ▸ | MEN1 | O00255 | 3/20 | 0.36 |
| ▸ | HTR1D | P28221 | 2/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.35 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439368 | 0.82 | CYP1A2 (0.43) | LMNAHTTALDH1A1L3MBTL1MITF | |
| SCHEMBL20439365 | 0.82 | CYP1A2 (0.43) | LMNAHTTALDH1A1L3MBTL1MITF | |
| SCHEMBL20439398 | 0.81 | AAK1 (0.43) | LMNAHTTALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL20439373 | 0.81 | AAK1 (0.43) | LMNAHTTALDH1A1L3MBTL1NPSR1 | |
| SCHEMBL20439386 | 0.79 | MAOB (0.41) | LMNAALDH1A1NPSR1KMT2AMEN1 | |
| SCHEMBL3608502 | 0.72 | FFAR1 (0.43) | KMT2AMEN1ATMGAAFFAR1 | |
| SCHEMBL20425205 | 0.72 | AOC3 (0.38) | LMNAHTTALDH1A1L3MBTL1MITF | |
| SCHEMBL12388688 | 0.72 | FFAR1 (0.44) | ALDH1A1KMT2AMEN1ATMGAA | |
| SCHEMBL9030426 | 0.69 | FFAR1 (0.43) | LMNAALDH1A1GAAFFAR1FFAR4 | |
| SCHEMBL14300877 | 0.69 | FFAR1 (0.46) | LMNAALDH1A1KMT2AMEN1ATM |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |