Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 4/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | RECQL | P46063 | 1/20 | 0.40 |
| ▸ | HTR1D | P28221 | 2/20 | 0.39 |
| ▸ | GPR34 | Q9UPC5 | 2/20 | 0.39 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.39 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | AR | P10275 | 1/20 | 0.38 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439317 | 0.90 | MAOB (0.38) | MAOBALDH1A1HTR1D | |
| SCHEMBL20439308 | 0.83 | MAOB (0.44) | MAOBKMT2AMEN1ALDH1A1RECQL | |
| SCHEMBL20439307 | 0.83 | MAOB (0.44) | MAOBKMT2AMEN1ALDH1A1RECQL | |
| SCHEMBL20439384 | 0.83 | PTPN1 (0.43) | KMT2AMEN1ALDH1A1GPR34FFAR1 | |
| SCHEMBL20439374 | 0.79 | LMNA (0.40) | KMT2AMEN1ALDH1A1HTR1DFFAR1 | |
| SCHEMBL5354486 | 0.76 | BCL2 (0.44) | PTPN1 | |
| SCHEMBL20439435 | 0.76 | BCL2 (0.44) | PTPN1 | |
| SCHEMBL20425144 | 0.76 | MAOB (0.43) | MAOBKMT2AMEN1ALDH1A1RECQL | |
| SCHEMBL5355437 | 0.76 | SCN4A (0.48) | MAOBKMT2ALMNAMAPT | |
| SCHEMBL20439319 | 0.76 | SCN4A (0.48) | MAOBKMT2ALMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |