Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AAK1 | Q2M2I8 | 6/20 | 0.43 |
| ▸ | FAAH | O00519 | 4/20 | 0.41 |
| ▸ | LMNA | P02545 | 3/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | PPARG | P37231 | 1/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 2/20 | 0.36 |
| ▸ | SLC6A9 | P48067 | 1/20 | 0.36 |
| ▸ | SLC6A5 | Q9Y345 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20439398 | 1.00 | AAK1 (0.43) | AAK1FAAHLMNAALDH1A1HTT | |
| SCHEMBL20439384 | 0.83 | PTPN1 (0.43) | AAK1ALDH1A1HTTPPARANPSR1 | |
| SCHEMBL20439374 | 0.81 | LMNA (0.40) | FAAHLMNAALDH1A1HTTL3MBTL1 | |
| SCHEMBL5354486 | 0.78 | BCL2 (0.44) | PPARGPPARA | |
| SCHEMBL20439435 | 0.78 | BCL2 (0.44) | PPARGPPARA | |
| SCHEMBL20439315 | 0.77 | PTPN1 (0.41) | AAK1PPARA | |
| SCHEMBL13306625 | 0.75 | FAAH (0.43) | AAK1FAAHLMNA | |
| SCHEMBL31751530 | 0.75 | MAPK1 (0.39) | AAK1FAAHLMNA | |
| SCHEMBL17625015 | 0.74 | GPR88 (0.56) | FAAHALDH1A1L3MBTL1PPARGPPARA | |
| SCHEMBL7562755 | 0.74 | GPR88 (0.56) | FAAHALDH1A1L3MBTL1PPARGPPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2018138739-A1 | NOVEL ANTIESTROGENIC HETEROCYCLIC COMPOUNDS | SUN PHARMA ADVANCED RESEARCH COMPANY LIMITED (IN) | 2018-08-02 | — | — | WO | disclosed |